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Baldness cure has arrived. Will cost an arm and a leg.

http://newsroom.cumc.columbia.edu/blog/2015/10/23/blocking-e...
snowy garrison
  10/25/15
I know someone who really needs this
Exciting chrome gunner giraffe
  10/25/15
Shrews MAF
adventurous sick idiot chad
  10/25/15
It is pretty crazy to think of how many medical advances we'...
contagious hell faggot firefighter
  10/25/15
What's even funnier is that it isn't like we went, "act...
olive slippery set
  10/25/15
Tbf, we're spending billions and still no closer to curing c...
Charcoal spot
  10/26/15
Between propecia, rogaine, and transplants, recedos have man...
ruby dog poop bawdyhouse
  10/25/15
this is 120 xo bro wisdom it thwarts progress
Excitant Karate
  10/25/15
http://i.ytimg.com/vi/iuHggzhSHNE/maxresdefault.jpg so fr...
ruby dog poop bawdyhouse
  10/25/15
looks better before
passionate tripping step-uncle's house
  10/26/15
it's all crap
snowy garrison
  10/25/15
baldmos on finasteride bald at 1/10th the rate they normally...
lascivious silver forum
  10/26/15
Sure - just take a drug that is meant for prostate issues, w...
Federal Apoplectic Candlestick Maker Whorehouse
  11/24/17
good headline
Zombie-like ungodly useless brakes
  10/25/15
It will cost about $7,000 a month. There will be bald middl...
snowy garrison
  10/25/15
"would u trade an arm + a leg for a full head of hair?&...
Zombie-like ungodly useless brakes
  10/25/15
...
snowy garrison
  10/25/15
Who cares? if you have good head you can just shave that shi...
Federal Apoplectic Candlestick Maker Whorehouse
  10/25/15
(bald prole)
snowy garrison
  10/26/15
...
Jet piazza depressive
  02/05/18
is the mouse ok? why is he bald in the first place? poor gu...
lavender hilarious roast beef
  10/26/15
...
Cracking wild voyeur
  02/20/18
nothing 'prole' about baldness men of northern european des...
passionate tripping step-uncle's house
  10/26/15
(Bald queer)
Aquamarine property kitty cat
  10/26/15
(swarthy Mediterranean meathead with a 3head)
passionate tripping step-uncle's house
  10/26/15
...
Jet piazza depressive
  02/05/18
Really? I have no data to back it up, but I feel like Medit...
Big Sinister Field Becky
  10/26/15
nah, some Italians and Spaniards go bald but most age within...
passionate tripping step-uncle's house
  10/26/15
I feel like I have never known a single Italian who was not ...
Big Sinister Field Becky
  10/26/15
I would be shocked if there was anyone balder than middle ea...
Doobsian vivacious area potus
  10/26/15
wtf is a central asian asians by far have the least amt of ...
passionate tripping step-uncle's house
  10/26/15
Afghans, etc. these dudes have a ton of Norwood-7s
Doobsian vivacious area potus
  10/26/15
soon
snowy garrison
  11/24/17
linmk?
stubborn queen of the night
  11/24/17
http://www.newsweek.com/chemical-mcdonalds-fries-may-cure-ma...
snowy garrison
  02/05/18
For hundreds of years the patent office refused to grant pat...
hairraiser tantric university
  11/24/17
Bet this discouraged people
snowy garrison
  02/20/18
...
ocher rehab
  02/20/18
Hairmo for life here Would be disappointed if tech cheapens...
Multi-colored angry stag film background story
  02/20/18


Poast new message in this thread



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Date: October 25th, 2015 11:29 AM
Author: snowy garrison

http://newsroom.cumc.columbia.edu/blog/2015/10/23/blocking-enzymes-in-hair-follicles-promotes-hair-growth/

Inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth, a new study from researchers at Columbia University Medical Center has found. The research was published today in the online edition of Science Advances.

In experiments with mouse and human hair follicles, Angela M. Christiano, PhD, and colleagues found that drugs that inhibit the Janus kinase (JAK) family of enzymes promote rapid and robust hair growth when applied to the skin.

The study raises the possibility that JAK inhibitors could be used to restore hair growth in forms of hair loss induced by male pattern baldness, and other types of hair loss that occur when hair follicles are trapped in a resting state. Two JAK inhibitors have been approved by the U.S. Food and Drug Administration. One is approved for treatment of blood diseases (ruxolitinib) and the other for rheumatoid arthritis (tofacitinib). Both are being tested in clinical trials for the treatment of plaque psoriasis and alopecia areata, an autoimmune disease that causes hair loss.

“What we’ve found is promising, though we haven’t yet shown it’s a cure for pattern baldness,” said Dr. Christiano. “More work needs to be done to test if JAK inhibitors can induce hair growth in humans using formulations specially made for the scalp.”

Christiano and her colleagues serendipitously discovered the effect of JAK inhibitors have on hair follicles when they were studying alopecia areata, a form of hair loss that’s caused by an autoimmune attack on the hair follicles. Christiano and colleagues reported last year that JAK inhibitors shut off the signal that provokes the autoimmune attack, and that oral forms of the drug restore hair growth in some people with the disorder.

In the course those experiments, Dr. Christiano noticed that mice grew more hair when the drug was applied to the skin than when the drug was given systemically. This suggested JAK inhibitors might be doing something to the hair follicles in addition to stopping the immune attack.

When the researchers looked more closely at normal mouse hair follicles, they found that JAK inhibitors rapidly awakened resting follicles out of dormancy. Hair follicles do not produce hair steadily, but cycle between dormant and active phases.

JAK inhibitors trigger the follicles’ normal reawakening process, the researchers found. Mice treated for five days with one of two JAK inhibitors sprouted new hair within 10 days, greatly accelerating the onset of hair growth. No hair grew on control mice within the same amount of time.

Mice results

Within 3 weeks, mice that received topical ruxolitinib or tofacitinib had regrown nearly all their hair (right photo; drug was applied only to the right side of the mouse). Little to no hair growth occurred in control mice during the same timeframe (left photo).

Image credit: From S. Harel et al., Sci. Adv. 1, e1500973 (2015). Distributed under a Creative

Commons Attribution Non Commercial License 4.0 (CC BY-NC). 10.1126/sciadv.1500973

“There aren’t many compounds that can push hair follicles into their growth cycle so quickly,” said Dr. Christiano. “Some topical agents induce tufts of hair here and there after a few weeks, but very few compounds have this potent an effect so quickly.” The drugs also produce longer hair from human hair follicles grown in culture and on skin grafted onto mice.

It’s likely that the drugs act on the same pathways in human follicles as they do in mice, suggesting they could induce new hair growth and extend the growth of existing hairs in humans.

However, whether JAK inhibitors can reawaken hair follicles that have been frozen in a resting state because of androgenetic alopecia (which causes male and female pattern baldness) or other forms of hair loss is still unknown. So far, all the experiments have been conducted in normal mice and human follicles. Experiments to address hair follicles affected by hair loss disorders are under way.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29038958)



Reply Favorite

Date: October 25th, 2015 12:32 PM
Author: Exciting chrome gunner giraffe

I know someone who really needs this

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039342)



Reply Favorite

Date: October 25th, 2015 11:30 AM
Author: adventurous sick idiot chad

Shrews MAF

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29038960)



Reply Favorite

Date: October 25th, 2015 11:37 AM
Author: contagious hell faggot firefighter

It is pretty crazy to think of how many medical advances we've made in the past hundred years but baldmos are still totally fukkked.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29038997)



Reply Favorite

Date: October 25th, 2015 11:42 AM
Author: olive slippery set

What's even funnier is that it isn't like we went, "actually, baldness is nbd. Spend all the money on curing cancer or whatever." Billions gets spent on trying to cure baldness, and we don't have any effective remedy. God or sim makers pwning us for our vanity

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039023)



Reply Favorite

Date: October 26th, 2015 9:26 PM
Author: Charcoal spot

Tbf, we're spending billions and still no closer to curing cancer

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048194)



Reply Favorite

Date: October 25th, 2015 11:42 AM
Author: ruby dog poop bawdyhouse

Between propecia, rogaine, and transplants, recedos have many tools at their disposal to thwart baldness

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039025)



Reply Favorite

Date: October 25th, 2015 11:42 AM
Author: Excitant Karate

this is 120 xo bro wisdom

it thwarts progress

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039026)



Reply Favorite

Date: October 25th, 2015 11:44 AM
Author: ruby dog poop bawdyhouse

http://i.ytimg.com/vi/iuHggzhSHNE/maxresdefault.jpg

so fresh so clean

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039030)



Reply Favorite

Date: October 26th, 2015 9:27 PM
Author: passionate tripping step-uncle's house

looks better before

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048200)



Reply Favorite

Date: October 25th, 2015 11:45 AM
Author: snowy garrison

it's all crap

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039031)



Reply Favorite

Date: October 26th, 2015 9:28 PM
Author: lascivious silver forum

baldmos on finasteride bald at 1/10th the rate they normally would. it's not a cure, but it should be good enough for most people

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048208)



Reply Favorite

Date: November 24th, 2017 4:05 PM
Author: Federal Apoplectic Candlestick Maker Whorehouse

Sure - just take a drug that is meant for prostate issues, with manifold side effects and play dice with your endocrine system instead of just shaving that shit

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#34763260)



Reply Favorite

Date: October 25th, 2015 11:38 AM
Author: Zombie-like ungodly useless brakes

good headline

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039005)



Reply Favorite

Date: October 25th, 2015 11:47 AM
Author: snowy garrison

It will cost about $7,000 a month. There will be bald middle class riots.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039039)



Reply Favorite

Date: October 25th, 2015 11:47 AM
Author: Zombie-like ungodly useless brakes

"would u trade an arm + a leg for a full head of hair?"

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039043)



Reply Favorite

Date: October 25th, 2015 12:18 PM
Author: snowy garrison



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039247)



Reply Favorite

Date: October 25th, 2015 12:38 PM
Author: Federal Apoplectic Candlestick Maker Whorehouse

Who cares? if you have good head you can just shave that shit or get a #1 and it looks good

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039386)



Reply Favorite

Date: October 26th, 2015 9:24 PM
Author: snowy garrison

(bald prole)

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048183)



Reply Favorite

Date: February 5th, 2018 3:58 PM
Author: Jet piazza depressive



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35331134)



Reply Favorite

Date: October 26th, 2015 9:33 PM
Author: lavender hilarious roast beef

is the mouse ok? why is he bald in the first place? poor guy

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048253)



Reply Favorite

Date: February 20th, 2018 1:12 AM
Author: Cracking wild voyeur



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35442663)



Reply Favorite

Date: October 26th, 2015 9:45 PM
Author: passionate tripping step-uncle's house

nothing 'prole' about baldness

men of northern european descent have baldness more than any other race/group

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048365)



Reply Favorite

Date: October 26th, 2015 9:50 PM
Author: Aquamarine property kitty cat

(Bald queer)

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048412)



Reply Favorite

Date: October 26th, 2015 9:54 PM
Author: passionate tripping step-uncle's house

(swarthy Mediterranean meathead with a 3head)

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048449)



Reply Favorite

Date: February 5th, 2018 3:59 PM
Author: Jet piazza depressive



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35331139)



Reply Favorite

Date: October 26th, 2015 9:55 PM
Author: Big Sinister Field Becky

Really? I have no data to back it up, but I feel like Mediterranean bros have the most.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048460)



Reply Favorite

Date: October 26th, 2015 9:57 PM
Author: passionate tripping step-uncle's house

nah, some Italians and Spaniards go bald but most age within thick locks

Nordics/Northern Euroes have thin as fuck fair colored hair

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048488)



Reply Favorite

Date: October 26th, 2015 10:00 PM
Author: Big Sinister Field Becky

I feel like I have never known a single Italian who was not balding.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048519)



Reply Favorite

Date: October 26th, 2015 9:59 PM
Author: Doobsian vivacious area potus

I would be shocked if there was anyone balder than middle eastern and central asian men

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048513)



Reply Favorite

Date: October 26th, 2015 10:22 PM
Author: passionate tripping step-uncle's house

wtf is a central asian

asians by far have the least amt of baldness of any race

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048866)



Reply Favorite

Date: October 26th, 2015 10:22 PM
Author: Doobsian vivacious area potus

Afghans, etc.

these dudes have a ton of Norwood-7s

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048876)



Reply Favorite

Date: November 24th, 2017 4:02 PM
Author: snowy garrison

soon

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#34763244)



Reply Favorite

Date: November 24th, 2017 4:03 PM
Author: stubborn queen of the night

linmk?

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#34763248)



Reply Favorite

Date: February 5th, 2018 3:47 PM
Author: snowy garrison

http://www.newsweek.com/chemical-mcdonalds-fries-may-cure-male-baldness-study-say-799439

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35331037)



Reply Favorite

Date: November 24th, 2017 4:04 PM
Author: hairraiser tantric university

For hundreds of years the patent office refused to grant patents on hair growing treatments bc it was considered as impossible as perpetual motion

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#34763252)



Reply Favorite

Date: February 20th, 2018 1:11 AM
Author: snowy garrison

Bet this discouraged people

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35442661)



Reply Favorite

Date: February 20th, 2018 1:11 AM
Author: ocher rehab



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35442662)



Reply Favorite

Date: February 20th, 2018 1:15 AM
Author: Multi-colored angry stag film background story

Hairmo for life here

Would be disappointed if tech cheapens and gets more effective for this

Hairmos should unite to destroy this tech but are too busy fucking to destroy the labs these baldmo incels are operating out of

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35442683)