\
  The most prestigious law school admissions discussion board in the world.
BackRefresh Options Favorite

Baldness cure has arrived. Will cost an arm and a leg.

http://newsroom.cumc.columbia.edu/blog/2015/10/23/blocking-e...
Appetizing Maniacal Puppy Degenerate
  10/25/15
I know someone who really needs this
Citrine house-broken tank mediation
  10/25/15
Shrews MAF
Disrespectful stimulating parlor reading party
  10/25/15
It is pretty crazy to think of how many medical advances we'...
green toaster
  10/25/15
What's even funnier is that it isn't like we went, "act...
cruel-hearted erotic famous landscape painting water buffalo
  10/25/15
Tbf, we're spending billions and still no closer to curing c...
massive aquamarine school cafeteria
  10/26/15
Between propecia, rogaine, and transplants, recedos have man...
Vibrant Bonkers Shrine Antidepressant Drug
  10/25/15
this is 120 xo bro wisdom it thwarts progress
razzle-dazzle seedy dog poop dingle berry
  10/25/15
http://i.ytimg.com/vi/iuHggzhSHNE/maxresdefault.jpg so fr...
Vibrant Bonkers Shrine Antidepressant Drug
  10/25/15
looks better before
Claret faggotry hell
  10/26/15
it's all crap
Appetizing Maniacal Puppy Degenerate
  10/25/15
baldmos on finasteride bald at 1/10th the rate they normally...
laughsome gaping national
  10/26/15
Sure - just take a drug that is meant for prostate issues, w...
Wine range
  11/24/17
good headline
Excitant smoky milk
  10/25/15
It will cost about $7,000 a month. There will be bald middl...
Appetizing Maniacal Puppy Degenerate
  10/25/15
"would u trade an arm + a leg for a full head of hair?&...
Excitant smoky milk
  10/25/15
...
Appetizing Maniacal Puppy Degenerate
  10/25/15
Who cares? if you have good head you can just shave that shi...
Wine range
  10/25/15
(bald prole)
Appetizing Maniacal Puppy Degenerate
  10/26/15
...
180 property legal warrant
  02/05/18
is the mouse ok? why is he bald in the first place? poor gu...
floppy balding kitty corn cake
  10/26/15
...
bespoke house
  02/20/18
nothing 'prole' about baldness men of northern european des...
Claret faggotry hell
  10/26/15
(Bald queer)
rebellious stage
  10/26/15
(swarthy Mediterranean meathead with a 3head)
Claret faggotry hell
  10/26/15
...
180 property legal warrant
  02/05/18
Really? I have no data to back it up, but I feel like Medit...
Soul-stirring pearl factory reset button lodge
  10/26/15
nah, some Italians and Spaniards go bald but most age within...
Claret faggotry hell
  10/26/15
I feel like I have never known a single Italian who was not ...
Soul-stirring pearl factory reset button lodge
  10/26/15
I would be shocked if there was anyone balder than middle ea...
wonderful brethren potus
  10/26/15
wtf is a central asian asians by far have the least amt of ...
Claret faggotry hell
  10/26/15
Afghans, etc. these dudes have a ton of Norwood-7s
wonderful brethren potus
  10/26/15
soon
Appetizing Maniacal Puppy Degenerate
  11/24/17
linmk?
Motley circlehead background story
  11/24/17
http://www.newsweek.com/chemical-mcdonalds-fries-may-cure-ma...
Appetizing Maniacal Puppy Degenerate
  02/05/18
For hundreds of years the patent office refused to grant pat...
contagious karate
  11/24/17
Bet this discouraged people
Appetizing Maniacal Puppy Degenerate
  02/20/18
...
Buff thriller dilemma dragon
  02/20/18
Hairmo for life here Would be disappointed if tech cheapens...
submissive gas station
  02/20/18


Poast new message in this thread



Reply Favorite

Date: October 25th, 2015 11:29 AM
Author: Appetizing Maniacal Puppy Degenerate

http://newsroom.cumc.columbia.edu/blog/2015/10/23/blocking-enzymes-in-hair-follicles-promotes-hair-growth/

Inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth, a new study from researchers at Columbia University Medical Center has found. The research was published today in the online edition of Science Advances.

In experiments with mouse and human hair follicles, Angela M. Christiano, PhD, and colleagues found that drugs that inhibit the Janus kinase (JAK) family of enzymes promote rapid and robust hair growth when applied to the skin.

The study raises the possibility that JAK inhibitors could be used to restore hair growth in forms of hair loss induced by male pattern baldness, and other types of hair loss that occur when hair follicles are trapped in a resting state. Two JAK inhibitors have been approved by the U.S. Food and Drug Administration. One is approved for treatment of blood diseases (ruxolitinib) and the other for rheumatoid arthritis (tofacitinib). Both are being tested in clinical trials for the treatment of plaque psoriasis and alopecia areata, an autoimmune disease that causes hair loss.

“What we’ve found is promising, though we haven’t yet shown it’s a cure for pattern baldness,” said Dr. Christiano. “More work needs to be done to test if JAK inhibitors can induce hair growth in humans using formulations specially made for the scalp.”

Christiano and her colleagues serendipitously discovered the effect of JAK inhibitors have on hair follicles when they were studying alopecia areata, a form of hair loss that’s caused by an autoimmune attack on the hair follicles. Christiano and colleagues reported last year that JAK inhibitors shut off the signal that provokes the autoimmune attack, and that oral forms of the drug restore hair growth in some people with the disorder.

In the course those experiments, Dr. Christiano noticed that mice grew more hair when the drug was applied to the skin than when the drug was given systemically. This suggested JAK inhibitors might be doing something to the hair follicles in addition to stopping the immune attack.

When the researchers looked more closely at normal mouse hair follicles, they found that JAK inhibitors rapidly awakened resting follicles out of dormancy. Hair follicles do not produce hair steadily, but cycle between dormant and active phases.

JAK inhibitors trigger the follicles’ normal reawakening process, the researchers found. Mice treated for five days with one of two JAK inhibitors sprouted new hair within 10 days, greatly accelerating the onset of hair growth. No hair grew on control mice within the same amount of time.

Mice results

Within 3 weeks, mice that received topical ruxolitinib or tofacitinib had regrown nearly all their hair (right photo; drug was applied only to the right side of the mouse). Little to no hair growth occurred in control mice during the same timeframe (left photo).

Image credit: From S. Harel et al., Sci. Adv. 1, e1500973 (2015). Distributed under a Creative

Commons Attribution Non Commercial License 4.0 (CC BY-NC). 10.1126/sciadv.1500973

“There aren’t many compounds that can push hair follicles into their growth cycle so quickly,” said Dr. Christiano. “Some topical agents induce tufts of hair here and there after a few weeks, but very few compounds have this potent an effect so quickly.” The drugs also produce longer hair from human hair follicles grown in culture and on skin grafted onto mice.

It’s likely that the drugs act on the same pathways in human follicles as they do in mice, suggesting they could induce new hair growth and extend the growth of existing hairs in humans.

However, whether JAK inhibitors can reawaken hair follicles that have been frozen in a resting state because of androgenetic alopecia (which causes male and female pattern baldness) or other forms of hair loss is still unknown. So far, all the experiments have been conducted in normal mice and human follicles. Experiments to address hair follicles affected by hair loss disorders are under way.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29038958)



Reply Favorite

Date: October 25th, 2015 12:32 PM
Author: Citrine house-broken tank mediation

I know someone who really needs this

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039342)



Reply Favorite

Date: October 25th, 2015 11:30 AM
Author: Disrespectful stimulating parlor reading party

Shrews MAF

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29038960)



Reply Favorite

Date: October 25th, 2015 11:37 AM
Author: green toaster

It is pretty crazy to think of how many medical advances we've made in the past hundred years but baldmos are still totally fukkked.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29038997)



Reply Favorite

Date: October 25th, 2015 11:42 AM
Author: cruel-hearted erotic famous landscape painting water buffalo

What's even funnier is that it isn't like we went, "actually, baldness is nbd. Spend all the money on curing cancer or whatever." Billions gets spent on trying to cure baldness, and we don't have any effective remedy. God or sim makers pwning us for our vanity

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039023)



Reply Favorite

Date: October 26th, 2015 9:26 PM
Author: massive aquamarine school cafeteria

Tbf, we're spending billions and still no closer to curing cancer

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048194)



Reply Favorite

Date: October 25th, 2015 11:42 AM
Author: Vibrant Bonkers Shrine Antidepressant Drug

Between propecia, rogaine, and transplants, recedos have many tools at their disposal to thwart baldness

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039025)



Reply Favorite

Date: October 25th, 2015 11:42 AM
Author: razzle-dazzle seedy dog poop dingle berry

this is 120 xo bro wisdom

it thwarts progress

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039026)



Reply Favorite

Date: October 25th, 2015 11:44 AM
Author: Vibrant Bonkers Shrine Antidepressant Drug

http://i.ytimg.com/vi/iuHggzhSHNE/maxresdefault.jpg

so fresh so clean

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039030)



Reply Favorite

Date: October 26th, 2015 9:27 PM
Author: Claret faggotry hell

looks better before

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048200)



Reply Favorite

Date: October 25th, 2015 11:45 AM
Author: Appetizing Maniacal Puppy Degenerate

it's all crap

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039031)



Reply Favorite

Date: October 26th, 2015 9:28 PM
Author: laughsome gaping national

baldmos on finasteride bald at 1/10th the rate they normally would. it's not a cure, but it should be good enough for most people

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048208)



Reply Favorite

Date: November 24th, 2017 4:05 PM
Author: Wine range

Sure - just take a drug that is meant for prostate issues, with manifold side effects and play dice with your endocrine system instead of just shaving that shit

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#34763260)



Reply Favorite

Date: October 25th, 2015 11:38 AM
Author: Excitant smoky milk

good headline

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039005)



Reply Favorite

Date: October 25th, 2015 11:47 AM
Author: Appetizing Maniacal Puppy Degenerate

It will cost about $7,000 a month. There will be bald middle class riots.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039039)



Reply Favorite

Date: October 25th, 2015 11:47 AM
Author: Excitant smoky milk

"would u trade an arm + a leg for a full head of hair?"

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039043)



Reply Favorite

Date: October 25th, 2015 12:18 PM
Author: Appetizing Maniacal Puppy Degenerate



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039247)



Reply Favorite

Date: October 25th, 2015 12:38 PM
Author: Wine range

Who cares? if you have good head you can just shave that shit or get a #1 and it looks good

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29039386)



Reply Favorite

Date: October 26th, 2015 9:24 PM
Author: Appetizing Maniacal Puppy Degenerate

(bald prole)

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048183)



Reply Favorite

Date: February 5th, 2018 3:58 PM
Author: 180 property legal warrant



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35331134)



Reply Favorite

Date: October 26th, 2015 9:33 PM
Author: floppy balding kitty corn cake

is the mouse ok? why is he bald in the first place? poor guy

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048253)



Reply Favorite

Date: February 20th, 2018 1:12 AM
Author: bespoke house



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35442663)



Reply Favorite

Date: October 26th, 2015 9:45 PM
Author: Claret faggotry hell

nothing 'prole' about baldness

men of northern european descent have baldness more than any other race/group

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048365)



Reply Favorite

Date: October 26th, 2015 9:50 PM
Author: rebellious stage

(Bald queer)

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048412)



Reply Favorite

Date: October 26th, 2015 9:54 PM
Author: Claret faggotry hell

(swarthy Mediterranean meathead with a 3head)

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048449)



Reply Favorite

Date: February 5th, 2018 3:59 PM
Author: 180 property legal warrant



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35331139)



Reply Favorite

Date: October 26th, 2015 9:55 PM
Author: Soul-stirring pearl factory reset button lodge

Really? I have no data to back it up, but I feel like Mediterranean bros have the most.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048460)



Reply Favorite

Date: October 26th, 2015 9:57 PM
Author: Claret faggotry hell

nah, some Italians and Spaniards go bald but most age within thick locks

Nordics/Northern Euroes have thin as fuck fair colored hair

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048488)



Reply Favorite

Date: October 26th, 2015 10:00 PM
Author: Soul-stirring pearl factory reset button lodge

I feel like I have never known a single Italian who was not balding.

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048519)



Reply Favorite

Date: October 26th, 2015 9:59 PM
Author: wonderful brethren potus

I would be shocked if there was anyone balder than middle eastern and central asian men

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048513)



Reply Favorite

Date: October 26th, 2015 10:22 PM
Author: Claret faggotry hell

wtf is a central asian

asians by far have the least amt of baldness of any race

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048866)



Reply Favorite

Date: October 26th, 2015 10:22 PM
Author: wonderful brethren potus

Afghans, etc.

these dudes have a ton of Norwood-7s

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#29048876)



Reply Favorite

Date: November 24th, 2017 4:02 PM
Author: Appetizing Maniacal Puppy Degenerate

soon

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#34763244)



Reply Favorite

Date: November 24th, 2017 4:03 PM
Author: Motley circlehead background story

linmk?

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#34763248)



Reply Favorite

Date: February 5th, 2018 3:47 PM
Author: Appetizing Maniacal Puppy Degenerate

http://www.newsweek.com/chemical-mcdonalds-fries-may-cure-male-baldness-study-say-799439

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35331037)



Reply Favorite

Date: November 24th, 2017 4:04 PM
Author: contagious karate

For hundreds of years the patent office refused to grant patents on hair growing treatments bc it was considered as impossible as perpetual motion

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#34763252)



Reply Favorite

Date: February 20th, 2018 1:11 AM
Author: Appetizing Maniacal Puppy Degenerate

Bet this discouraged people

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35442661)



Reply Favorite

Date: February 20th, 2018 1:11 AM
Author: Buff thriller dilemma dragon



(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35442662)



Reply Favorite

Date: February 20th, 2018 1:15 AM
Author: submissive gas station

Hairmo for life here

Would be disappointed if tech cheapens and gets more effective for this

Hairmos should unite to destroy this tech but are too busy fucking to destroy the labs these baldmo incels are operating out of

(http://www.autoadmit.com/thread.php?thread_id=3026560&forum_id=2#35442683)