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bitcoin zillionaires, toss some $$ to http://www.sens.org, save billions of ppl

http://www.sens.org they're trying to cure aging and actu...
POTUS Kobach forcibly ejecting the last DREAMER
  01/13/18
Curing aging without mass castration seems like a terrible i...
purveyor of filth
  01/13/18
?
POTUS Kobach forcibly ejecting the last DREAMER
  01/13/18
Death is a gift from G-d and any that fight it surely deserv...
pepito
  01/13/18
does this apply to any attempt to extend human life?
POTUS Kobach forcibly ejecting the last DREAMER
  01/13/18
what would be the point?
Oh, you travel?
  01/14/18
...
.,.,.,,,.,,.,.,.,,.,.,.,.,.,,.,.,.,.
  01/13/18
...
Oh, you travel?
  01/13/18
...
alzabo
  01/14/18
...
nonstop knifemare buffet
  01/14/18
hey guise lets help boomers live longer so they can boom MOR...
.,.,.,,,.,,.,.,.,,.,.,.,.,.,,.,.,.,.
  01/13/18
...
alzabo
  01/14/18
This is 20 to 30 year timeline stuff. Most boomers won't rea...
POTUS Kobach forcibly ejecting the last DREAMER
  01/14/18
senescent cell removal by itself extends lifespan in mice by...
"'"'"''"""
  01/20/18
...
ETH dunking on Skadden Assoc (joeybank)
  01/14/18
SENS is likely taking the wrong path. The induced pluripoten...
"'"'"''"""
  01/14/18
Feinerman: There is growing evidence that epigenetic changes...
POTUS Kobach forcibly ejecting the last DREAMER
  01/14/18
I agree with him that stochastic epigenetic drift is probabl...
"'"'"''"""
  01/14/18
...
spaceporn2525
  01/14/18
looks like some other bitcoin bros were generous http://...
POTUS Kobach forcibly ejecting the last DREAMER
  01/16/18
Print January 16, 2018 18:30 ET | Source: SENS Resear...
POTUS Kobach forcibly ejecting the last DREAMER
  01/16/18
it's odd this doesn't attract more money. i would have thoug...
"'"'"''"""
  01/20/18
Aubrey has talked about this on various occasions. One issue...
POTUS Kobach forcibly ejecting the last DREAMER
  01/20/18
i expect this will change once people start seeing robust re...
"'"'"''"""
  01/20/18
That's the hope.
POTUS Kobach forcibly ejecting the last DREAMER
  01/20/18


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Date: January 13th, 2018 9:11 PM
Author: POTUS Kobach forcibly ejecting the last DREAMER

http://www.sens.org

they're trying to cure aging and actually have a serious, comprehensive plan to do it with many preftigious ppl on board

SENS actually got some bitcoin $$$ recently too but basically has an unlimited need for cash since they're doing basic scientific research on so many problems

http://www.sens.org/outreach/press-releases/srf-receives-1m-btc-from-the-pineapple-fund



(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150122)



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Date: January 13th, 2018 9:30 PM
Author: purveyor of filth

Curing aging without mass castration seems like a terrible idea

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150200)



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Date: January 13th, 2018 10:02 PM
Author: POTUS Kobach forcibly ejecting the last DREAMER

?

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150325)



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Date: January 13th, 2018 10:04 PM
Author: pepito

Death is a gift from G-d and any that fight it surely deserve the hell they will get

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150332)



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Date: January 13th, 2018 10:06 PM
Author: POTUS Kobach forcibly ejecting the last DREAMER

does this apply to any attempt to extend human life?

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150342)



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Date: January 14th, 2018 12:01 AM
Author: Oh, you travel?

what would be the point?

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150927)



Reply Favorite

Date: January 13th, 2018 11:56 PM
Author: .,.,.,,,.,,.,.,.,,.,.,.,.,.,,.,.,.,.




(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150902)



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Date: January 13th, 2018 11:57 PM
Author: Oh, you travel?



(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150908)



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Date: January 14th, 2018 12:00 AM
Author: alzabo



(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150921)



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Date: January 14th, 2018 12:20 AM
Author: nonstop knifemare buffet



(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35151004)



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Date: January 13th, 2018 11:57 PM
Author: .,.,.,,,.,,.,.,.,,.,.,.,.,.,,.,.,.,.


hey guise lets help boomers live longer so they can boom MORE!

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35150904)



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Date: January 14th, 2018 12:24 AM
Author: alzabo



(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35151024)



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Date: January 14th, 2018 10:53 AM
Author: POTUS Kobach forcibly ejecting the last DREAMER

This is 20 to 30 year timeline stuff. Most boomers won't really benefit much...

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35152544)



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Date: January 20th, 2018 7:10 PM
Author: "'"'"''"""


senescent cell removal by itself extends lifespan in mice by up to 35%. there are several senolytic candidate drugs now that could possibly extend median lifespan by 1-3 decades. drugs like dasatinib are not something the average boomer is going to want to take without human trials, but it seems likely that relatively benign senolytics will be available in less than 10 years.

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35198974)



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Date: January 14th, 2018 12:05 PM
Author: ETH dunking on Skadden Assoc (joeybank)



(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35152980)



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Date: January 14th, 2018 12:48 AM
Author: "'"'"''"""


SENS is likely taking the wrong path. The induced pluripotent stem cell research should be taken as strong evidence that epigenetic changes are the primary cause of aging. the research being done on cyclic use of reprogramming factors to undo epigenetic changes (which isn't part of the SENS research project) is more likely to lead to large increases in maximum lifespan than anything in the SENS program.

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35151131)



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Date: January 14th, 2018 10:52 AM
Author: POTUS Kobach forcibly ejecting the last DREAMER

Feinerman: There is growing evidence that epigenetic changes are highly organized and may be one of the causes of ageing. What do you think? Maybe should we consider epigenetic changes as another type of damage in SENS model, calling EpiSENS?

de Grey: We need to be much more precise with definitions in order to answer your question. Epigenetic changes can be classified into two main classes: shift and noise. Shift means changes that occur in a coordinated manner among all cells of a given type and tissue, whereas noise means changes that occur in some such cells but not others, increasing the variability of that type of cell. Shifts are caused by some sort of program (genetic changes to the cell's environment), so yes, they can potentially be reversed by restoring the environment and putting the program into reverse. Noise, on the other hand, is not reversible. And we have for several years worked on determining whether it happens enough to matter in a currently normal lifetime. We have not got to a definitive answer, but it's looking though no, epigenetic noise accumulates too slowly to matter, other than maybe for cancer (which, of course, we are addressing in other ways).

Feinerman: Should we use reprogramming factors to reverse the epigenetic program?

de Grey: Probably not. There may be some benefits in doing so, as a way to restore the numbers of certain types of stem cells, but we can always do that by other methods (especially by direct stem cell transplantation), so I don't think we will ever actually need to dedifferentiate cells in vivo.

https://www.fightaging.org/archives/2017/12/an-interview-with-aubrey-de-grey-focused-on-the-science-of-rejuvenation-therapies/



(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35152542)



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Date: January 14th, 2018 3:48 PM
Author: "'"'"''"""


I agree with him that stochastic epigenetic drift is probably not very important (like stochastic nuclear DNA damage doesn't matter in a normal human lifespan). There are, however, highly regular epigenetic changes that are strongly predictive of mortality. Old cells that are reprogrammed show almost complete reversal of the aged phenotype. Aging is mostly programmed.

His concern with in vivo reprogramming is probably related to cancer (if cells completely lose their identity cancer formation is probable). The study done using temporary application of cellular reprogramming factors suggests this isn't necessarily a major problem.

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35154689)



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Date: January 14th, 2018 11:24 AM
Author: spaceporn2525



(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35152696)



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Date: January 16th, 2018 8:14 PM
Author: POTUS Kobach forcibly ejecting the last DREAMER

looks like some other bitcoin bros were generous

http://www.globenewswire.com/news-release/2018/01/16/1290183/0/en/SENS-Research-Foundation-2017-Year-End-Fundraiser-Achieves-Over-5-Million-in-Donations.html

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35171564)



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Date: January 16th, 2018 8:14 PM
Author: POTUS Kobach forcibly ejecting the last DREAMER

Print

January 16, 2018 18:30 ET | Source: SENS Research Foundation

MOUNTAIN VIEW, Calif., Jan. 16, 2018 (GLOBE NEWSWIRE) -- SENS Research Foundation (SRF), a leading Silicon Valley nonprofit focused on diseases of aging, announced today that it received over $5 Million in donations during its year end fundraising campaign. These donations included $1 Million in Bitcoin from the Pineapple Fund; $1 Million in Bitcoin from an anonymous donor; and $2.4 Million in Ethereum from Vitalik Buterin, the cofounder of Ethereum and Bitcoin Magazine.

“SENS Research Foundation is pleased by the strong support we have received from members of the tech community who are innovative leaders in utilizing cryptocurrency. We appreciate their support and look forward to partnering with them going forward,” said Aubrey de Grey, CSO.

“We are very grateful to all of our donors for their incredible support of our Year End Campaign,” said Jerri Barrett, VP of Outreach. “Our initial campaign goal was $250,000. We were thrilled to receive over 1400 donations totaling over $5 million in just ten weeks.”

“Achieving this level of donation in such a short period of time shows that the momentum SENS Research Foundation has achieved is continuing,” said Michael Kope, CEO. “We are looking forward to engaging even more of the tech community in our work and to continue to accelerate our progress through the expansion of our research programs. Their support makes this growth possible.”

To learn more and to donate to the SENS Research Foundation please go to www.sens.org.

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35171567)



Reply Favorite

Date: January 20th, 2018 7:04 PM
Author: "'"'"''"""


it's odd this doesn't attract more money. i would have thought there would be a few billionaires looking to extend their lives.

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35198957)



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Date: January 20th, 2018 7:15 PM
Author: POTUS Kobach forcibly ejecting the last DREAMER

Aubrey has talked about this on various occasions. One issue is the wife often hates it. So like a handful of dumb shrews who'd rather give to causes that get them more cocktail party status points will be responsible for significantly more deaths than Adolf Hitler

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35198994)



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Date: January 20th, 2018 7:20 PM
Author: "'"'"''"""


i expect this will change once people start seeing robust rejuvenation from senolytics. the idea of curing or substantially reversing aging still sounds fanciful to most.

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35199010)



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Date: January 20th, 2018 7:42 PM
Author: POTUS Kobach forcibly ejecting the last DREAMER

That's the hope.

(http://www.autoadmit.com/thread.php?thread_id=3858762&forum_id=2#35199161)